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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS1
All Species:
14.85
Human Site:
S506
Identified Species:
32.67
UniProt:
O75925
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75925
NP_057250.1
651
71836
S506
P
H
Q
A
S
P
V
S
R
T
P
S
L
P
A
Chimpanzee
Pan troglodytes
XP_523109
766
83908
S621
P
H
Q
A
S
P
V
S
R
T
P
S
L
P
A
Rhesus Macaque
Macaca mulatta
XP_001082800
642
70843
R498
H
Q
A
S
P
V
S
R
T
P
S
L
P
A
V
Dog
Lupus familis
XP_535524
651
71773
S506
P
H
Q
A
S
P
V
S
R
T
P
S
L
P
A
Cat
Felis silvestris
Mouse
Mus musculus
O88907
651
71599
S506
P
H
Q
A
S
P
V
S
R
T
P
S
L
P
A
Rat
Rattus norvegicus
O70260
628
68345
A484
A
L
P
G
S
K
G
A
L
T
S
G
H
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
S605
L
N
L
P
H
Q
A
S
P
V
S
R
T
P
S
Chicken
Gallus gallus
NP_001026627
564
62782
K420
W
A
P
M
R
S
K
K
E
V
Q
E
V
T
T
Frog
Xenopus laevis
NP_001079161
649
71676
I505
L
Q
H
Q
A
S
P
I
S
R
T
P
S
L
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
P599
L
A
A
Q
K
T
P
P
Q
Q
K
K
K
T
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
E534
Q
E
K
V
G
Y
Q
E
K
N
I
I
P
M
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.9
98.6
99.6
N.A.
98
58.6
N.A.
82.2
82.9
87
N.A.
N.A.
N.A.
N.A.
24
N.A.
Protein Similarity:
100
84.9
98.6
99.8
N.A.
98.7
72
N.A.
84.2
85
94.3
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
13.3
N.A.
13.3
0
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
100
20
N.A.
26.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
19
37
10
0
10
10
0
0
0
0
0
10
37
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
10
10
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
10
0
10
0
0
0
0
10
0
0
0
% G
% His:
10
37
10
0
10
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
10
10
0
0
0
% I
% Lys:
0
0
10
0
10
10
10
10
10
0
10
10
10
0
10
% K
% Leu:
28
10
10
0
0
0
0
0
10
0
0
10
37
10
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
37
0
19
10
10
37
19
10
10
10
37
10
19
46
19
% P
% Gln:
10
19
37
19
0
10
10
0
10
10
10
0
0
10
0
% Q
% Arg:
0
0
0
0
10
0
0
10
37
10
0
10
0
0
0
% R
% Ser:
0
0
0
10
46
19
10
46
10
0
28
37
10
0
19
% S
% Thr:
0
0
0
0
0
10
0
0
10
46
10
0
10
19
10
% T
% Val:
0
0
0
10
0
10
37
0
0
19
0
0
10
0
10
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _